Dienstag, 5. Mai 2026

The Daily

Handhygiene-Tag. Kaffee zählt trotzdem.

Wien heute: ☀️ sonnig, aktuell 16°C (gefühlt 16°C). Wind 5 km/h, Luftfeuchtigkeit 59%. Sonnenaufgang 05:30, Sonnenuntergang 20:14.

NBA

Two Game 1s, no score talk

Monday night brought two second-round Game 1s: 76ers-Knicks and Timberwolves-Spurs. Both sit inside Robert's spoiler window, so this stays to matchups and viewing priority only. Wikihoops gives Spurs-Wolves the stronger replay signal; Knicks-Sixers is the completist opener, with no scores, winners, stats or updated series state here.
Source: Wikihoops + NBA.com

Knicks-Sixers starts with guard pressure

New York opened the second round with Brunson-Maxey as the clean pressure point. Embiid's health and Mikal Bridges' defensive role are the pre-tip variables to watch without revealing anything from Game 1.
Source: NBA.com

Edwards status shapes Spurs-Wolves

Anthony Edwards was upgraded to questionable before Game 1 after being cleared for on-court work. That made Spurs-Wolves an availability story before tip-off, not only a Wembanyama-Gobert frontcourt postcard.
Source: NBA.com / AP

Thunder-Lakers waits on availability

Thunder-Lakers begins Tuesday, outside the already-played Monday spoiler window. The setup is Oklahoma City's continuity and depth against a Lakers team managing Luka Doncic's status around LeBron James and Austin Reaves.
Source: NBA.com

Biotech & Pharma

Europe's pharma access gap gets sharper

Boehringer Ingelheim is warning that Europe risks yielding pharma innovation to the US and China if pricing and reimbursement rules stay slow. Hernexeos is the concrete case: a lung-cancer drug invented in Europe has launched in the US, China and Japan while European access waits on reimbursement and comparator-trial demands. The strategic issue is whether Europe can reward domestic invention before companies learn to launch elsewhere first.
Source: FT

First PROTAC reaches breast cancer

The FDA approved Arvinas and Pfizer's Veppanu for ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer after endocrine therapy. It is the first marketed PROTAC, but the commercial path is still unsettled while the partners seek another backer.
Source: BioPharma Dive

Kennedy moves on SSRI deprescribing

Robert F. Kennedy Jr. announced trainings, reimbursement mechanisms and clinical guidelines for SSRI deprescribing and non-drug interventions. The policy is concrete and contested: the NYT cites 16.6% adult SSRI use in 2026, while psychiatric groups warn against broad overprescribing claims.
Source: NYT

Chiesi buys an oral HAE launch

Chiesi agreed to buy KalVista for $1.9bn to take over Ekterly, an oral on-demand hereditary angioedema medicine. Rare-disease launches still draw buyers when sales are visible: KalVista had nearly $50mn in Ekterly revenue last year.
Source: BioPharma Dive

Science / Immuno-Oncology

In-vivo CAR-T gets a first myeloma signal

A Nature Medicine phase 1 study generated anti-BCMA CAR-T cells inside patients with relapsed or refractory multiple myeloma. The early value is feasibility: in-vivo generation could bypass ex-vivo manufacturing and lymphodepletion. The caution is equally important, because the dataset is only five patients and belongs in the proof-of-concept bucket.
Source: Nature Medicine

CAR-PRISM tests earlier myeloma intervention

CAR-PRISM moves cilta-cel into high-risk smoldering multiple myeloma, where the question is delaying progression rather than last-line rescue. The endpoint set is useful: complete response, MRD negativity, PFS and time to progression.
Source: Nature Medicine

One noisy night stresses the vasculature

Road-noise exposure in bedrooms measurably affected heart and vessel function after a single night. Faster heart rate and reduced vessel elasticity make traffic noise a physiology story, not only an annoyance story.
Source: Spiegel+

China doubles down on wind power

China is leaning harder into wind power while oil remains expensive and Middle East tensions keep supply risk alive. The science angle is systems-level: clean-energy capacity is becoming a strategic hedge against fossil-fuel shocks.
Source: NYT

Travel

Vier seltsame Gärten für Italien-Umwege

Surreale Gärten - vier Kunstorte in Italien
Nutzwert - Umwege statt Standard-Checkliste
Timing - aktueller NYT-Travel-Guide vom 04.05.2026

Für Roberts Italien-Fokus ist das stark, weil es nicht noch einmal Rom, Venedig oder Amalfi sortiert. Es sind Orte, die eine Route persönlicher machen, ohne gleich eine ganze Reise umzubauen.
Source: NYT

Venedig ohne Biennale-Burnout

Die FT nimmt die Biennale als Planungsproblem ernst: weniger Pflichtprogramm, mehr Pausen. Für Venedig ist das die bessere Reisehaltung, weil die Stadt sonst schnell nur noch aus Warteschlangen und schlechtem Timing besteht.
Source: FT

Venedig-Tagestrips brauchen Gebührencheck

Venedig verlangt an 60 Tagen bis Ende Juli wieder Eintritt von Tagesgästen: 10 Euro regulär, 5 Euro bei Buchung mindestens drei Tage vorher. Wer nur einen Tagesausflug plant, sollte den Zugangskalender vor der Route prüfen.
Source: Spiegel+

Kerosinangst kürzt erste Flugpläne

Airlines streichen Flüge, weil die Sorge um Treibstoffknappheit nach dem Iran-Schock wächst. Für Reisende ist das die praktische Seite der Energiestory: Verbindungen und Preise können sich ändern, bevor man den Makroeffekt merkt.
Source: FT