DONNERSTAG, 30. APRIL 2026

The Daily

Kapital, Courts, Playoffs, Krebsmedizin und ein Wiener Maibaum.

Wien heute: ☀️ sonnig, aktuell 2°C (gefühlt 0°C). Tagesband 2–13°C, Wind Nord/Nordost 7–15 km/h, Luftfeuchtigkeit morgens 55%. Sonnenaufgang 05:38, Sonnenuntergang 20:07.

NBA

Three Game 5s, one replay-first morning

Last night’s playoff board had Orlando–Detroit, Toronto–Cleveland and Houston–Lakers in first-round Game 5s. Keep it clean: no scores, winners, new series states or box-score lines here. Wikihoops put the early games in solid-but-not-mandatory territory, while the late Lakers–Rockets window was the natural first replay check before opening any scoreboard. If Robert has time for one game, start there and stay away from recap pages until after viewing.
Source: NBA.com / Wikihoops

Injury board cuts both ways in L.A.

Austin Reaves returned from a nine-game oblique absence for the Lakers’ Game 5 rotation. Kevin Durant, meanwhile, was ruled out for Houston with a left ankle sprain after missing practice. The useful angle is pregame structure: creation, spacing and bench responsibility changed before tip-off.
Source: NBA.com / AP

Minnesota’s injury math gets brutal

Anthony Edwards is out at least a week with a hyperextended left knee and bone bruise. Donte DiVincenzo’s Achilles injury removes another starter from Minnesota’s guard rotation. Even if the Wolves move on, the next series begins with usage, defense and late-clock creation under stress.
Source: NBA.com

Warriors pause the Kerr decision

Steve Kerr met Joe Lacob and Mike Dunleavy for two hours, but ESPN reports no resolution on whether he continues as Warriors coach. The next checkpoint is early May. Golden State also carries the May 10 lottery as a major roster lever.
Source: ESPN

Biotech & Pharma

FDA tests live trial review, starting in oncology

The FDA is piloting real-time review of clinical-trial data, beginning with oncology studies from AstraZeneca and Amgen. The mechanism matters more than the software vendor: reviewers see trial data while studies are still running, potentially reducing the slow document exchange after database lock. If the oncology proof of concept works, it could change sponsor-reviewer cadence for high-priority cancer programs.
Source: STAT

J&J gets priority review in warm AIHA

Johnson & Johnson says the FDA granted Priority Review for nipocalimab in warm autoimmune hemolytic anemia. The heme/immunology hook is an FcRn blocker aimed at pathogenic IgG. ENERGY data are the anchor: durable hemoglobin response and fatigue improvement.
Source: FT

PureTech leans into myeloid-malignancy optionality

PureTech’s annual update puts Gallop Oncology’s LYT-200 in relapsed/refractory high-risk MDS back on the map. It is formally a finance update, but the medical signal is clearer: externally financed hub-and-spoke oncology assets are being pushed toward later development and FDA-trial-design conversations.
Source: FT

Insilico adds another AI-discovered IND

Insilico says a rentosertib inhalation formulation received CDE IND clearance, its 13th AI-pipeline program to reach IND. The useful read is not “AI discovered drug” as slogan, but how fibrosis, oncology and immunology programs keep moving through the Pharma.AI workflow into regulatory filings.
Source: FT

Science / Immuno-Oncology

HER2 bispecific moves into first-line gastric review

Jazz says the FDA accepted and granted Priority Review to a zanidatamab sBLA for first-line HER2-positive gastric, GEJ and esophageal adenocarcinoma combinations. The science angle is not just another filing: a HER2 bispecific is being reviewed with chemo, and in one arm with PD-1 blockade, under RTOR after HERIZON-GEA-01. The August PDUFA date makes this a near-term checkpoint for HER2 biology moving earlier in GI cancer.
Source: FT

AstraZeneca’s quarter is really a pipeline map

AstraZeneca’s Q1 update works as a compressed IO and ADC map. The relevant items are Imfinzi activity in HCC and gastric settings, Enhertu filings, Datroway movement and a Pinetree bispecific-antibody degrader option. It shows where commercial oncology and next-modality science are starting to overlap.
Source: FT

Incyte queues DLBCL and TGFβR2×PD-1 readouts

Incyte flags frontMIND Phase 3 data for tafasitamab plus lenalidomide/R-CHOP in newly diagnosed DLBCL. The same update points to INCA33890, a TGFβR2×PD-1 program in MSS colorectal cancer. That gives the day a useful heme-to-solid-tumor IO bridge ahead of ASCO.
Source: FT

Keytruda’s access problem is now an IO systems question

SPIEGEL’s Keytruda investigation pulls the section away from pure company wrappers. Pembrolizumab is framed as a checkpoint-inhibitor breakthrough whose PD-1/PD-L1 biology, Nobel-prize mechanism and indications in triple-negative breast cancer, melanoma and NSCLC now collide with affordability. The anchor is stark: 17 doses for one patient at €91,717.38 and more than €2bn German statutory-insurance spend in 2025.
Source: SPIEGEL

Wien für Kinder

Maibaum ohne Landpartie

Ottakring macht den Maibaum heute zur einfachen Familienoption: Bastel- und Spielstationen, Karussell, Trampolin und eine große Rutsche, bevor der Baum steht. Der praktische Vorteil ist wichtiger als die Folklore. Man kann nach der Kita hin, bleibt draußen und geht wieder, sobald die Energie kippt.
Source: ViennaInside

Der Prater macht den 1. Mai kindertauglich

Das Prater-Maifest hat morgen auf der Kaiserwiese eine klare Kinderschiene: ORF Kids SpieleZoo, Stylingbox, Spielecke, Sportstationen und Helfer-Wiens-Programm. Das ist kein Geheimtipp, aber ein brauchbarer Feiertagsplan. Gut, wenn der Tag offen bleiben soll und Eintrittshürden nerven würden.
Source: Heute.at

Der MQ-Mai hat echte Kinderkultur

Das MQ listet für Mai mehrere Termine, die nicht nur Beiprogramm sind: BRUDI & BÄR im DSCHUNGEL WIEN, BALL, BAUM, TAUBE und später der KinderKulturParcours. Der Wert liegt im Vorplanen. Ein naher Theater-/Konzerttermin plus ein größerer freier Familientag reichen als Kalenderanker.
Source: MuseumsQuartier Wien

Falters 1.-Mai-Regal ist der Regenplan

Falters aktuelle Themen bündeln 1.-Mai-Material, Kinderbücher und Wien-für-Kinder-Titel auf einer Seite. Das ist keine Veranstaltungsliste. Als Plan B für Buchhandlung, Lesen und langes Wochenende funktioniert es trotzdem besser als ein beliebiger Shop-Scroll.
Source: FALTER